Benzyl Alcohol

Benzyl alcohol · aromatic-solvent and preservative reference material

Confirm on released-lot COA · target, verify batch COACAS 100-51-6RUO

Research statusEstablished chemical identity; RUO laboratory reagent

Supplied formSmall aromatic alcohol; non-peptide laboratory reagent

Lead timeConfirmed with quote

Benzyl Alcohol — Lot-specific clear liquid; confirm colour, clarity and particulate limits on the released-batch COA

Benzyl Alcohol — Lot-specific clear liquid; confirm colour, clarity and particulate limits on the released-batch COA · Representative packaging image · verify the ordered lot

Representative packaging image · verify the ordered lot

Decision summary

Key benefits

Laboratory applications include solvent and preservative-reference studies, analytical standards, formulation screening and compatibility testing
Its bacteriostatic contribution depends on concentration and the complete formulation; it neither sterilizes material nor guarantees peptide stability.

Published research context is presented for literature orientation only. It is not a dosing, treatment or human-use instruction.

Qualification data

Specifications to confirm against the released lot

CAS: 100-51-6
Formula: Not applicable to the supplied material
Molecular weight: 108.14 g/mol
Appearance: Lot-specific clear liquid; confirm colour, clarity and particulate limits on the released-batch COA
Purity: Confirm on released-lot COA · target, verify batch COA
Storage: Follow the released lot SDS, COA and stability statement for the specified grade and container. Control heat, ignition sources, moisture and container compatibility as directed; do not transfer an opened-vial period from a diluted finished product to neat benzyl alcohol.
MOQ: On request
Lead time: Confirmed with quote

Qualification matrix

Identity, purity and content are separate release questions.

Identity

Confirm the stated molecule and supplied form. Start with the matching batch COA; request sequence-level evidence only when the buyer's written procedure requires it and availability or a separate scope has been agreed.

Purity

Review RP-HPLC method conditions, wavelength, integration and related-peak handling. A percentage without the method is not enough.

Content

Net peptide content is not the same as gross lyophilized powder weight. Ask which assay supports the stated amount and whether water/counter-ion is addressed.

Stability

Define long-term storage and transit exposure separately. Cold-chain can be quoted when the buyer’s risk assessment requires it and adds cost.

Research context

What researchers study about Benzyl Alcohol

Benzyl alcohol is an aromatic alcohol, C₇H₈O, molecular weight 108.14 g/mol, CAS 100-51-6 and PubChem CID 244. It is used in chemistry as a solvent and in some validated formulations as a preservative or excipient. Those uses do not make neat RUO benzyl alcohol a sterile diluent, an injectable product or a universally compatible peptide preservative. Procurement should define grade, quantitative assay, water, impurity profile, container and intended method.

Analytical reference, laboratory solvent, preservative-mechanism research, formulation screening and material-compatibility studies
These are laboratory applications, not clinical indications.

Mechanism context

The question the literature is testing

At suitable formulation concentrations, benzyl alcohol can inhibit microbial growth through effects on membranes and proteins. It is not a sterilant. Literature also discusses membrane-related local-anesthetic effects, but those clinical formulation observations are not a use claim for neat RUO material. Compatibility and function must be demonstrated in the exact formulation.

Evidence map

Research routes and exposure context

Evidence tierAnalytical / laboratory context

Research areaLaboratory ancillaries

Routes reported in sources

No administration route applies

Dose / exposure contextProtocol-specific; verify the cited primary source

Routes and exposure contexts summarize cited studies or approved finished-product labels. They are not instructions for administering this RUO material; no customer dose is provided.

Evidence boundaries

Compatibility, limitations and decision context

Follow the released-lot SDS and institutional controls for exposure, ventilation, ignition sources, spills and waste
Benzyl alcohol can be harmful through inappropriate exposure, and systemic exposure has caused severe neonatal toxicity in historical preserved medical products
This toxicology context does not establish a patient dose or acceptable injectable concentration
The RUO reagent is not for human or veterinary administration.

Interactions reported in the literature

Compatibility depends on concentration, pH, other excipients, peptide/protein sequence, container and analytical endpoint
Benzyl alcohol can affect proteins, cells, membranes and some packaging materials
No universal peptide compatibility or mixing recommendation is made.

Literature context is not a supplier release result or human-use instruction. Follow your institution's approved laboratory risk assessment.

Factory batch documentation

Benzyl Alcohol factory batch COAs

Benzyl Alcohol 3 mL Factory batch COA protected preview

Benzyl Alcohol3 mL · WHJLP-BA3-260716-C

Benzyl Alcohol 10 mL Factory batch COA protected preview

Benzyl Alcohol10 mL · WHJLP-BA10-260716-C

Representative records, refreshed periodically

Published COAs show representative factory batches and may not be the latest available. For a current quote or shipment, our sales team can confirm the applicable lot and provide its COA.

Independent testing, arranged on request

Third-party reports are not routinely published. If independent verification is required, we can agree the laboratory, method, acceptance criteria and remedy before testing. If the agreed specification is not met, an appropriate resolution—including a refund where applicable—can be discussed under the agreed terms. Unless otherwise agreed in writing, the buyer pays the cost of this optional testing.

Help reviewing your COA

Need help reading a factory COA or third-party report? Our sales team can clarify test items, specifications and how the results relate to the lot under discussion.

Ask for the current packet, not a generic certificate

Require identity by suitable orthogonal methods, quantitative assay, water, related substances and relevant residuals, density or other grade-specific tests, visible-particle and colour limits, container compatibility, lot traceability and stability basis
If microbial, sterile or endotoxin claims are needed for a downstream process, they require separate validated tests; they cannot be inferred from chemical purity.

Released-batch COARP-HPLC result and method contextIdentity result appropriate to the moleculeWater / counter-ion context where relevantSDS and handling statementAdditional testing scoped on request

Available fills

Quote the fill and pack configuration you need

Reference SKUFillBase pack

BA-03ML3 ml10 vials

BA-10ML10 ml10 vials

Handling

Storage in the lab and temperature during transit are different decisions

Follow the released lot SDS, COA and stability statement for the specified grade and container. Control heat, ignition sources, moisture and container compatibility as directed; do not transfer an opened-vial period from a diluted finished product to neat benzyl alcohol.

State destination, season, acceptable transit exposure and whether your protocol requires insulated or cold-chain service. Additional temperature-control cost is quoted explicitly.

Buyer FAQ

Terms to settle before the purchase order

Can a buyer arrange third-party testing?+

Yes. Testing must be performed by a mutually accepted, established specialist laboratory. Fee allocation, specification, sampling, method and acceptance rule must be agreed before testing; if an agreed independent result shows nonconformance, the remedy follows the signed order terms. Unless otherwise agreed in writing, the buyer pays the cost of this optional testing.

Does HPLC purity prove peptide content?+

No. Chromatographic purity describes the relative peak profile under a stated method. Identity, water, counter-ion, residual solvents and assay/content may require separate methods.

Is cold-chain shipping always required?+

Not always. Heat can accelerate degradation, especially during summer and long transit. Cold-chain reduces exposure but raises cost. State the destination and stability risk so the right service can be quoted.

How are payment terms handled?+

Available methods and milestones depend on order value, destination and project type. The pro forma invoice should state currency, bank details, fees, payment milestones and the release condition.

Why must the testing laboratory understand peptide chemistry?+

Free-base and salt forms, hydrophilic and hydrophobic sequences, aggregation and adsorption can change sample preparation and method suitability. Use a laboratory experienced with the molecule class.

External qualification references

WHO good storage and distribution practices IATA Temperature Control Regulations ISO/IEC 17025 laboratory competence 21 CFR 211.84 component testing and supplier COA controls

These are buyer-qualification references, not claims that this RUO material is regulated, certified or released under those frameworks. Applicability depends on the buyer's workflow and jurisdiction.

Selected sources

Literature behind the research context

PubChem CID 244 and CAS 100-51-6 support chemical identity and core physical properties. Current DailyMed labels provide formulation-specific context for approved products containing benzyl alcohol. Gershanik et al., NEJM 1982, and related CDC reporting document neonatal systemic toxicity from preserved medical products. These sources do not provide instructions for using neat RUO benzyl alcohol in humans.

01
The gasping syndrome and benzyl alcohol poisoning
New England Journal of Medicine · 1982 · peer-reviewed original research (landmark clinical case series)
Open source
02
Neonatal deaths associated with use of benzyl alcohol -- United States
Morbidity and Mortality Weekly Report (MMWR), Centers for Disease Control · 1982 · regulatory/public health surveillance report (CDC MMWR)
Open source
03
Safety Assessment of Benzyl Alcohol, Benzoic Acid and its Salts, and Benzyl Benzoate
International Journal of Toxicology (Cosmetic Ingredient Review Expert Panel) · 2017 · expert panel safety assessment / systematic review (Cosmetic Ingredient Review)
Open source
04
Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate
International Journal of Toxicology (Cosmetic Ingredient Review) · 2001 · expert panel safety assessment (Cosmetic Ingredient Review, foundational report)
Open source
05
Benzyl alcohol attenuates the pain of lidocaine injections and prolongs anesthesia
Journal of Dermatologic Surgery and Oncology · 1994 · peer-reviewed original research (randomized double-blind controlled trial)
Open source
06
Bacteriostatic Water for Injection, USP - Full Prescribing Information
Pfizer/Hospira official product labeling · 2026 · regulatory document / official manufacturer prescribing information (FDA-approved label)
Open source
07
Bacteriostatic Water for Injection, USP -- Structured Product Label
DailyMed (NIH National Library of Medicine) · 2026 · regulatory document (FDA structured product label, hosted by NIH/NLM)
Open source

Benzyl Alcohol

Key benefits

Specifications to confirm against the released lot

Identity, purity and content are separate release questions.

What researchers study about Benzyl Alcohol

The question the literature is testing

Research routes and exposure context

Compatibility, limitations and decision context

Interactions reported in the literature

Benzyl Alcohol factory batch COAs

Ask for the current packet, not a generic certificate

Quote the fill and pack configuration you need

Storage in the lab and temperature during transit are different decisions

Terms to settle before the purchase order

Literature behind the research context

The gasping syndrome and benzyl alcohol poisoning

Neonatal deaths associated with use of benzyl alcohol -- United States

Safety Assessment of Benzyl Alcohol, Benzoic Acid and its Salts, and Benzyl Benzoate

Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate

Benzyl alcohol attenuates the pain of lidocaine injections and prolongs anesthesia

Bacteriostatic Water for Injection, USP - Full Prescribing Information

Bacteriostatic Water for Injection, USP -- Structured Product Label

Compare adjacent molecules and documentation needs.

Bacteriostatic Water

Sterile Water

Acetic Acid Water

Saline