Oxytocin Acetate

Name: Oxytocin Acetate
Brand: LyoPep

Cyclic disulfide-bridged oxytocin research reference · acetate form must be confirmed by lot

Lot-specific · Batch COACAS 50-56-6RUO

Batch COA

MOQ1 kit (10 vials) per SKU

Supplied formNonapeptide (cyclic, disulfide-bridged)

Lead time14–21 days

Oxytocin Acetate — Lot-specific lyophilized research peptide; confirm colour and physical form on the released-lot COA

Oxytocin Acetate — Lot-specific lyophilized research peptide; confirm colour and physical form on the released-lot COA · Representative packaging image · verify the ordered lot

Representative packaging image · verify the ordered lot

Decision summary

Key benefits

Defensible research value includes OXTR pharmacology, smooth-muscle and calcium-signalling models, receptor selectivity versus vasopressin receptors, neurobehavioural model design, disulfide-folding analytics and reference-standard qualification
Approved finished-drug efficacy cannot be transferred to bulk material, and “love hormone,” trust, autism, weight-loss or wellness claims are not established uses of this RUO lot.

Published research context is presented for literature orientation only. It is not a dosing, treatment or human-use instruction.

Qualification data

Specifications to confirm against the released lot

CAS: 50-56-6
Formula: C₄₃H₆₆N₁₂O₁₂S₂
Molecular weight: 1007.2 g/mol
Appearance: Lot-specific lyophilized research peptide; confirm colour and physical form on the released-lot COA
Purity: Lot-specific chromatographic purity plus quantitative peptide content; confirm disulfide state, acetate/counterion, water and related peptides separately · target, verify batch COA
Storage: Follow the released-batch storage statement and SDS. Confirm post-opening or prepared-sample stability against the laboratory's validated protocol.
MOQ: 1 kit (10 vials) per SKU
Lead time: 14–21 days

PubChem CID 439302

Qualification matrix

Identity, purity and content are separate release questions.

Identity

Confirm the stated molecule and supplied form. Start with the matching batch COA; request sequence-level evidence only when the buyer's written procedure requires it and availability or a separate scope has been agreed.

Purity

Review RP-HPLC method conditions, wavelength, integration and related-peak handling. A percentage without the method is not enough.

Content

Net peptide content is not the same as gross lyophilized powder weight. Ask which assay supports the stated amount and whether water/counter-ion is addressed.

Stability

Follow the storage condition stated on the batch COA or label from receipt onward.

Research context

What researchers study about Oxytocin Acetate

Oxytocin is a cyclic disulfide-bridged nonapeptide acting at the oxytocin receptor and, at some exposures, related vasopressin receptors. Named synthetic oxytocin injection finished drugs are approved for specific obstetric uses, while many intranasal social-cognition claims remain investigational and have produced mixed or negative trial results. Those approvals and studies do not make bulk oxytocin acetate an approved medicine. Lot qualification must resolve cyclic disulfide connectivity, peptide identity, acetate or other counterions and quantitative content.

Appropriate laboratory contexts include OXTR binding and signalling, receptor-selectivity studies, smooth-muscle and reproductive-tissue models, neurobehavioural models with rigorous controls, disulfide-folding and related-peptide analytics, and reference-standard work
Approved clinical indications belong to named finished drugs, not this bulk material.

Mechanism context

The question the literature is testing

Oxytocin activates OXTR-dependent G-protein and calcium signalling in appropriate models and can cross-react with vasopressin receptors depending on concentration and system. Central behavioural effects are context-dependent and not reducible to a universal bonding response. Correct intramolecular Cys1–Cys6 disulfide connectivity is central to the native cyclic structure; reduced, mispaired or intermolecular species must be analytically distinguished.

Evidence map

Research routes and exposure context

Evidence tierApproved finished-product context

Research areaHormonal research

Routes reported in sources

Intranasal

Dose / exposure contextProtocol-specific; verify the cited primary source

Routes and exposure contexts summarize cited studies or approved finished-product labels. They are not instructions for administering this RUO material; no customer dose is provided.

Evidence boundaries

Compatibility, limitations and decision context

Not for human or veterinary administration
Named finished-drug labels contain serious obstetric, haemodynamic and water-intoxication warnings that require clinical monitoring; they do not establish safety of bulk RUO material
Incorrect disulfide state, content or counterion, degradation, aggregation, contamination and unvalidated endotoxin or sterility are material research risks.

Interactions reported in the literature

No human combination guidance applies
SSRI, benzodiazepine, alcohol, selank, PT-141 and kisspeptin combination claims were removed from the RUO decision content
Laboratory receptor cross-reactivity or combination studies require defined systems, single-agent controls and concentration matrices.

Literature context is not a supplier release result or human-use instruction. Follow your institution's approved laboratory risk assessment.

Batch documentation

Oxytocin Acetate batch COAs

Laboratory: Manufacturer's QC laboratoryTests: HPLC purity · MS identity · endotoxin · fill amount

2 mg
5 mg
10 mg

Previews are blurred on purpose so the documents cannot be reused; third-party reports show their first page only. Sales sends the clear full version for the product and strength you ask about.

Independent test fails? Full refund.

Representative records, refreshed periodically

Published COAs show recent representative batches and may not be the newest. For a quote or shipment, sales confirms the lot and sends its COA.

Third-party reports, added progressively

Previews of the first page of third-party reports are on our Quality page and on the matching product pages; sales sends the full report on request. You can also send any vial from your order to an independent laboratory of your choice. Unless agreed otherwise in writing, the buyer pays for optional testing.

Help reviewing your COA

Need help reading a batch COA or third-party report? Sales can explain the test items, specifications and how the results relate to the lot under discussion.

On every batch COA: HPLC purity · MS identity · endotoxin · fill amount · Verify LyoPep

Third-party reports for Oxytocin Acetate

Reports from Qorix (tjqxgd.com), a third-party analytical laboratory in Tianjin, China: HPLC purity and MS identity of the sample tested.

Laboratory: Third-party laboratoryTests: HPLC purity · MS identity

2 mg
5 mg

Previews are blurred on purpose so the documents cannot be reused; third-party reports show their first page only. Sales sends the clear full version for the product and strength you ask about.

Ask for the current packet, not a generic certificate

Require sequence and Cys1–Cys6 disulfide-connectivity evidence, intact mass, peptide mapping where appropriate, chromatographic purity and related peptides, quantitative peptide content on a stated basis, acetate and other counterions, water, residual solvents, reduction or oxidation products, aggregation or particulates where relevant, container integrity and lot-specific stability
Appearance or a single HPLC result is insufficient.

Batch COA for the released lotHPLC purity with method contextMS identity resultEndotoxin resultFill amount (measured content per vial)SDS and handling statement

Available fills

Quote the fill and pack configuration you need

Reference SKUFillBase pack

OXYT22 mg10 vials

OT55 mg10 vials

OT1010 mg10 vials

Other format

Also available as a nasal spray (US stock)

Black 10 mL nasal spray bottle with a clear cap — 10 mL nasal spray bottle

Besides lyophilized vials, Oxytocin Acetate is also supplied as a nasal spray solution, shipped from our US stock.

Strengths: 2 mg
Bottle sizes: 10 mL or 20 mL
Minimum order: 10 bottles per strength and bottle size
Ships from: Our US stock

Handling

Plan storage before the parcel arrives

Follow the released-batch storage statement and SDS. Confirm post-opening or prepared-sample stability against the laboratory's validated protocol.

State the destination and timing so receipt can be planned, then move the material into its stated storage condition on arrival.

Buyer FAQ

Terms to settle before the purchase order

Can a buyer arrange third-party testing?+

Yes. You can send any vial from your order to an independent laboratory of your choice. If you want the laboratory, specification, sampling, method and acceptance rule agreed with us before testing, sales confirms them in writing. Unless otherwise agreed in writing, the buyer pays the cost of this optional testing.

What if my own lab test shows the product is out of specification?+

Send any vial from your order to an independent laboratory of your choice. If the report shows the product does not meet the specification on its COA — purity below the stated minimum, or an identity that does not match — share the report with our sales team and we refund that product in full.

Does HPLC purity prove peptide content?+

No. Chromatographic purity describes the relative peak profile under a stated method. Identity, water, counter-ion, residual solvents and assay/content may require separate methods.

How should material be stored after delivery?+

Move it into the storage condition stated on the batch COA or label as soon as it arrives, and record the package condition on receipt.

How are payment terms handled?+

Available methods and milestones depend on order value, destination and project type. The pro forma invoice should state currency, bank details, fees, payment milestones and the release condition.

Why must the testing laboratory understand peptide chemistry?+

Free-base and salt forms, hydrophilic and hydrophobic sequences, aggregation and adsorption can change sample preparation and method suitability. Use a laboratory experienced with the molecule class.

External qualification references

WHO good storage and distribution practices ISO/IEC 17025 laboratory competence 21 CFR 211.84 component testing and supplier COA controls

These are buyer-qualification references, not claims that this RUO material is regulated, certified or released under those frameworks. Applicability depends on the buyer's workflow and jurisdiction.

Selected sources

Literature behind the research context

Primary boundaries include the FDA Pitocin label for the named finished injection and its clinical warnings, NIH PubChem molecular identity records, and peer-reviewed receptor and clinical-trial literature. Finished-drug doses, storage and approved indications are evidence context only. Large intranasal social-cognition trials with negative primary endpoints prevent one-sided efficacy claims.

01
Oxytocin increases trust in humans
Nature · 2005 · peer-reviewed original research
Open source
02
Does oxytocin increase trust in humans? A critical review of research
Perspectives on Psychological Science · 2015 · critical review
Open source
03
The neurobiological impact of oxytocin in mental health disorders: a comprehensive review
Annals of Medicine and Surgery (London) · 2025 · comprehensive review
Open source
04
The effects of oxytocin administration on social and routinized behaviors in autism: A preregistered systematic review and meta-analysis
Psychoneuroendocrinology · 2024 · preregistered systematic review and meta-analysis
Open source
05
Optimal dose of oxytocin to improve social impairments and repetitive behaviors in autism spectrum disorders: meta-analysis and dose-response meta-analysis of randomized controlled trials
Frontiers in Psychiatry · 2025 · meta-analysis and dose-response meta-analysis
Open source
06
WHO Recommendations: Uterotonics for the Prevention of Postpartum Haemorrhage
World Health Organization (NCBI Bookshelf reproduction) · 2018 · regulatory/global health body recommendation
Open source
07
Oxytocin is an age-specific circulating hormone that is necessary for muscle maintenance and regeneration
Nature Communications · 2014 · peer-reviewed original research
Open source
08
Pitocin (Oxytocin Injection, USP) Prescribing Information
US Food and Drug Administration (accessdata.fda.gov) · 2021 · regulatory document (FDA drug label)
Open source

Product FAQ

Questions buyers ask about Oxytocin Acetate

Why is oxytocin’s disulfide state essential to identity testing?+

Oxytocin contains an intramolecular Cys1–Cys6 disulfide bridge that defines the cyclic peptide. Qualification should combine intact mass with a method that distinguishes oxidized cyclic material from reduced, mispaired or intermolecular-disulfide species, such as peptide mapping and a qualified chromatographic comparison. A nominal mass or HPLC area value alone does not prove correct disulfide connectivity.

How should free oxytocin and oxytocin acetate be reported?+

The peptide moiety, acetate or other counterions, water and assay basis must be separated. Formula C₄₃H₆₆N₁₂O₁₂S₂ and about 1007.19 Da describe the oxytocin peptide reference, while an acetate-containing material has additional counterion mass and potentially variable stoichiometry. The COA should state whether peptide content is reported as-is, anhydrous, free-peptide equivalent or salt.

What should a laboratory request beyond a purity percentage?+

Request sequence and disulfide-connectivity evidence, intact mass, peptide mapping where appropriate, chromatographic purity and related-peptide profile, quantitative peptide content, acetate and other counterions, water, residual solvents, oxidation or reduction products, aggregation or particulates where relevant, container integrity and lot-specific stability. Endotoxin, bioburden and sterility are separate study-dependent attributes.

Evidence before order

Oxytocin Acetate

Key benefits

Specifications to confirm against the released lot

Identity, purity and content are separate release questions.

What researchers study about Oxytocin Acetate

The question the literature is testing

Research routes and exposure context

Compatibility, limitations and decision context

Interactions reported in the literature

Oxytocin Acetate batch COAs

Third-party reports for Oxytocin Acetate

Ask for the current packet, not a generic certificate

Quote the fill and pack configuration you need

Also available as a nasal spray (US stock)

Plan storage before the parcel arrives

Terms to settle before the purchase order

Literature behind the research context

Oxytocin increases trust in humans

Does oxytocin increase trust in humans? A critical review of research

The neurobiological impact of oxytocin in mental health disorders: a comprehensive review

The effects of oxytocin administration on social and routinized behaviors in autism: A preregistered systematic review and meta-analysis

Optimal dose of oxytocin to improve social impairments and repetitive behaviors in autism spectrum disorders: meta-analysis and dose-response meta-analysis of randomized controlled trials

WHO Recommendations: Uterotonics for the Prevention of Postpartum Haemorrhage

Oxytocin is an age-specific circulating hormone that is necessary for muscle maintenance and regeneration

Pitocin (Oxytocin Injection, USP) Prescribing Information

Questions buyers ask about Oxytocin Acetate

Buyer intelligence

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